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Document 2421
DOCN M94A2421
TI Risk factors and characteristics of HIV+ antenatal women, Bangkok,
Thailand. Bangkok Perinatal HIV Transmission Study.
DT 9412
AU Mangclaviraj Y; Chaisilwattana P; Siriwasin W; Roongpisuthipong A;
Shaffer N; Rajvithi Hospital, MOPH.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):308 (abstract no. PC0162). Unique
Identifier : AIDSLINE ICA10/94370154
AB OBJECTIVES: To determine risk factors for HIV seropositivity and
characteristics at study entry of pregnant women registering for
antenatal care in Bangkok. METHODS: At 2 large hospitals in Bangkok with
regular antenatal HIV counseling and testing, HIV-infected pregnant
women are enrolled for prospective followup in a perinatal transmission
study; HIV-negative control women are enrolled for a single
questionnaire evaluation to help assess risk factors and characteristics
associated with HIV seropositivity. RESULTS: Through Dec 1993, 293 HIV+
and 293 HIV- women were enrolled in antenatal clinic. Compared to HIV-
women, HIV+ women were younger (22 vs. 24 yrs; p < 0.01) and were more
likely to have: a history of STD's (20% vs. 4%; p < 0.01); worked as a
sex worker (8% vs. 1%; p < 0.01); a history of > or = 3 sex partners
(15% vs. 3%; p < 0.01). However, 80% of HIV+ women and 96% of HIV- women
had no evident risk factor for HIV infection. The median CD4 count of
HIV+ women at study entry was 430 (range 100-1290); 2% of women had CD4
counts < 200 and 66% had CD4 counts < 500. HIV+ women reported
significantly more symptoms of weight loss (13% vs. 4%), fatigue (11%
vs. 1%), and vaginal candidiasis (32% vs. 17%) than HIV- women. None of
the HIV+ women had signs of AIDS. Enrollment and risk factor analyses
are ongoing. CONCLUSIONS: Most HIV+ women presenting to antenatal care
did not have recognizable risk factors for HIV infection. While most
HIV+ women were asymptomatic, consistent with a recent and rapidly
expanding epidemic, immunosuppression, as assessed by CD4 counts, was
higher than expected.
DE Adult Female Human HIV Infections/DIAGNOSIS *HIV Seropositivity
Pregnancy *Pregnancy Complications, Infectious/DIAGNOSIS Risk Factors
Thailand MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).